个人简介：杨永寿，博士，硕士生导师。2010年毕业于石河子大学食品质量与安全专业，获工学学士学位。2013 年至 2018 年在日本广岛大学统合生命研究科留学，先后获得硕士和博士学位。博士毕业后先后在日本庆应大学和东京大学从事博士后研究工作，期间获得日本文部省“外国人特别研究员”（JSPS）项目资助。2021 年回国后在安徽大学从事教学科研工作。目前主要在功能性食品、肠道健康、益生菌/益生、微生物资源发掘等领域从事相关研究工作。借助多组学、生物信息学、基因编辑、发酵工程等技术手段，围绕功能食品、益生菌等开展基础科学研究和应用技术转化。近年在 Frontiers in Nutrition、Foods、Life Sciences、Journal of Functional Foods、Journal of Future Foods 等主流国际学术期刊发表论文20 余篇。同时担任International Journal of Molecular Sciences等多篇杂志审稿人。

主要研究方向:

（1）   肠道微生态

（2）   多组学分析

（3）   益生菌

（4）   肝损伤

获得人才称号:安徽省青年“百人计划”

主要科研论文(2018- )：

1.       Shi, L., Cao, X., Yang, B., Wang, Y., & Yang, Yongshou Yang*. (2025). Mulberry Leaf Extracts Ameliorate Aflatoxin B(1)-Induced Liver Injury by Modulating Nrf2 Pathway and Gut Microbiota. Journal of Food Science, 90(10), e70600. https://doi.org/10.1111/1750-3841.70600

2.       Yongshou Yang*, Xuejing Cao, Norihisha Kato, Yongzhong Wang. Gut Bacteroides fragilis in health and diseases: An updated review. Journal of Future Foods, 2025.

3.       Cao, X., Cheng, J., Yongshou Yang*, Wang, J, & Wang, Y. Arginine-derived carbon dots with antioxidant activity for treating aflatoxin B1-induced liver injury via Nrf2/Keap1 and NLRP3 pathways in mice. Life Sciences, 364, 123430, 2025. https://doi.org/10.1016/j.lfs.2025.123430

4.       Braga, J. D., Yongshou Yang, Nagao, T., Kato, N., Yanaka, N., Nishio, K., Okada, M., Kuroda, M., Yamaguchi, S., & Kumrungsee, T. (2025). Fructooligosaccharides and Aspergillus enzymes increase brain GABA and homocarnosine by modulating microbiota in adolescent mice. NPJ Science of Food, 9(1), 48. https://doi.org/10.1038/s41538-025-00383-1

5.       Yongshou Yang, Kumrungsee T, Okazaki Y, Watanabe T, Inoue J, Iguchi T, Fukuda S, Kuroda M, Nishio K, Yamaguchi S, et al. Potential Roles of Exogenous Proteases and Lipases as Prebiotics. Nutrients, 17(5):924, 2025. https://doi.org/10.3390/nu17050924

6.       Yongshou Yang, Yaqi Wang, Xuejing Cao, Lixiao Shi, Yongzhong Wang. Lactobacillus buchneri ameliorates obesity-related disorders induced by high-fat and high-cholesterol diet in mice. Food and Humanity, 3, 100317, 2024.

7.       Yongshou Yang, Jia, H., Ando, C., Kato, H., Kumrungsee, T., Kato, N., Kimoto, A., Fukuda, S., Kuroda, M., Nishio, K., & Yamaguchi, S.. Exogenous Penicillium camemberti Lipase Preparation Exerts Prebiotic-like Effects by Increasing Cecal Bifidobacterium and Lactobacillus Abundance in Rats. Fermentation, 9(3), 227, 2023.

8.       Yongshou Yang, Huijuan Jia, Weida Lyu, Kyohei Furukawa, Yukio Hasebe and Hisanori Kato. Dietary Eggshell Membrane Powder Improves Survival Rate and Ameliorates Gut Dysbiosis in Interleukin-10 Knockout Mice. Frontiers in Nutrition, 9, 2022.

9.       Yongshou Yang, Thanutchaporn Kumrungsee, Norihisa Kato, Shinji Fukuda, Manabu Kuroda, and Shotaro Yamaguchi, Aspergillus-Derived Cellulase Preparation Exhibits Prebiotic-like Effects on Gut Microbiota in Rats. Fermentation, 8(2), 71, 2022.

10.    Yongshou Yang, Thanutchaporn Kumrungsee, Norihisa Kato, Shinji Fukuda, Manabu Kuroda, Shotaro Yamaguchi, Supplemental Aspergillus Lipase and Protease Preparations Display Powerful Bifidogenic Effects and Modulate the Gut Microbiota Community of Rats. Fermentation, 7, 294, 2021.

11.    Yongshou Yang, Rikako Fukui, Huijuan Jia, Hisanori Kato. Amaranth supplementation improves hepatic lipid dysmetabolism and modulates gut microbiota in mice fed a high-fat diet. Foods, 10 (6), 1259, 2021.

12.    Yongshou Yang, Kan Takahara, Akiko Kimoto, Norihisa Kato, Fumio Shimamoto. Consumption of low-dose of ethanol suppresses colon tumorigenesis in 1,2-Dimethylhydrazine-treated rats. Journal of Nutritional Science and Vitaminology, 65 (5), 443-450, 2019.

13.    Yongshou Yang, Norihisa Kato, Thanutchaporn Kumrungsee, Manabu Kuroda, Shotaro

Yamaguchi, Feeding Aspergillus protease preparation combined with adequate protein diet to rats increases levels of cecum gut-protective amino acids, partially linked to Bifidobacterium and Lactobacillus. Bioscience, Biotechnology, and Biochemistry,11, 1-11, 2019.

14.    Yongshou Yang, Tsuyoshi Kameda, Hideyuki Aoki, Dwi Eva Nirmagustina, Akane Iwamoto, Thanutchaporn Kumrungsee, Norihisa Kato, Noriyuki Yanaka, and Yukako Okazaki. The effects of tempe fermented with Rhizopus microsporus, Rhizopus oryzae, or Rhizopus stolonifer on the colonic luminal environment in rats. Journal of Functional Foods, 49, 162-167, 2018. (Q1)

15.    Yongshou Yang*, Jinhu Tian, and Bo Yang. Targeting gut microbiome: A novel and potential therapy for autism. Life Sciences, 194, 111-119, 2018. (Q1)

16.    Jiayue Yang, Yongshou Yang, Manami Ishii, Mayuko Nagata, Wanping Aw, Nozomu Obana, Masaru Tomita, Nobuhiko Nomura, Shinji Fukuda. Does gut microbiota modulate host physiology through polymicrobial biofilms? Microbes and Environments, 35(3), 2020.

17.    Churan Fu, Yongshou Yang, Thanutchaporn Kumrungsee, Akiko Kimoto, Hanae Izu, Norihisa Kato. Low-Dose Ethanol Has Impacts on Plasma Levels of Metabolites Relating to Chronic Disease Risk in SAMP8 mice. Journal of Nutritional Science and Vitaminology, 66 (6), 553-560, 2020.

18.    Dwi Eva Nirmagustina, Abdelkrim Khedara, Djamila Benouchenne, Karima Boubekri, Yongshou  Yang, Sofya Suidasari, Thanutchaporn Kumrungsee, Norihisa Kato. High-dose D-glucosamineconsumption increases serum and cecum levels of ammonia and ethanol and causes bacterial overgrowth in rats. Food Science and Technology Research, 25 (1), 107-113, Jan, 2019.

19.    Tsuyoshi Kameda, Hideyuki Aoki, Yongshou Yang, Dwi Eva Nirmagustina, Akane Iwamoto, Thanutchaporn Kumrungsee, Norihisa Kato, Noriyuki Yanaka. Beneficial effects of dietary tempeh prepared with Rhizopus stolonifer on liver function in rats fed with high-fat Diet. Journal of Nutritional Science and Vitaminology, 64 (5), 379-383, Oct, 2018.

20.    Masahiro Yamaguchi, Yongshou Yang, Misaki Ando, Thanutchaporn Kumrungsee, Norihisa Kato, Yukako Okazaki. Increased intestinal ethanol after consumption of fructo-oligosaccharides in the rats. Biomedical Reports, 9 (5), 427-432, Sep, 2018.

21.    Dwi Eva Nirmagustina, Yongshou Yang, Thanutchaporn Kumrungsee, Noriyuki Yanaka, Norihisa Kato. Gender difference and dietary supplemental vitamin B6: impact on colon luminal environment. Journal of Nutritional Science and Vitaminology, 64 (2), 116-128, Apr, 2018.